Uterine fibroids—common benign tumors that grow in the wall of the uterus—are most common during a woman’s 30s and 40s, usually until she reaches menopause. This unmistakable pattern is suspected to parallel estrogen levels that rise prior to menopause but then taper off. Excess estrogen circulating in the body may also play a role in uterine fibroid growth.
To naturally manage hormone levels, women are encouraged to swap out processed foods for whole foods that may help balance estrogen levels and inhibit tumor growth. Calcium-D-glucarate, a naturally-occurring mineral in several fruits and vegetables, has been found to aid in ridding the body of excess estrogen.
The body detoxifies excess hormones by first metabolizing them in the liver and then excreting them through the feces or urine.
According to a 2016 paper published by Kunc, Gabrych, and Witkowski, certain gut bacteria make an enzyme called β‐glucuronidase that can inhibit this detox process.1 The authors explain that at high levels, β‐glucuronidase makes the body hold on to excess hormones—reabsorbing them back into the body instead of excreting them—causing estrogen levels to rise. High levels of β‐glucuronidase have been linked with a greater risk of estrogen-dependent cancers.1
Supplementation with calcium-D-glucarate has been seen to weaken β‐glucuronidase activity, in turn helping the body excrete more estrogen.1 High fiber diets, like vegetarian, have also been seen to reduce β‐glucuronidase in the feces—which results in more estrogen being excreted and less circulating in the body.1
As with any treatment, supplementing with calcium-D-glucarate should always first be discussed with a doctor. This helpful mineral can be found in fiber-rich foods such as oranges, grapefruits, apples, and cruciferous vegetables like broccoli, kale, and cabbage. Incorporating these foods into your everyday meals and snacks can be an easy way to help balance hormones and naturally fight fibroids.
ABOUT THE AUTHOR Alicia Armeli is a Health Freelance Writer, Registered Dietitian Nutritionist, and Certified Holistic Life Coach. She has master’s degrees in English Education and Nutrition. Through her writing, she empowers readers to live optimally by building awareness surrounding issues that impact health and wellbeing. In addition to writing, she enjoys singing, traveling abroad and volunteering in her community.
- Kunc, M., Gabrych, A., & Witkowski, J. M. (2016). Microbiome impact on metabolism and function of sex, thyroid, growth and parathyroid hormones. Acta Biochimica Polonica. 63(2): 189-201. doi: 10.18388/abp.2015_1093